| Studies on Fasting 2
International Journal of Ramadan Fasting
Research 2:18, 1998
Abstracts of Selected Articles on
Ramadan Fasting, 1997-98,
Compiled by M.Z.A. Nomani 1997:
Title: Fasting during Ramadan
induces a marked increase in high-density lipoprotein cholesterol and
decrease in low-density lipoprotein cholesterol.
Authors: Ahmed Adlouni1, Nosreddine
Ghalim2, Abdellah Benslimane2, Jean Mechel Lecerf 3and Rachid Saile1
Institution:
1 Laboratoire de recherches sur les lipoproteines, Department de
Biologie, Faculte des Sciences Ben M'sik, and
2 Laboratoire des Lipoproteines, Insitut Pasteur du Maroc,
Casabalanca, Morocco;
3 Service de Nutrition, Institut Pasteur de Lille, France
Source: Annals of Nutrition and
Metabolism, 41: 242-249, 1997.
Abstract:
The study was conducted on 32 healthy adult male volunteers. A significant
decrease (7.9%, p<0.001) in serum total cholesterol and triglycerides
(30%, p<0.001)concentration during Ramadan as compared with the
pre-fasting period. By the end of Ramadan , serum HDL cholesterol had
markedly increased (14.3%, p<0.001) and remained elevated one month
after Ramadan, in contrast LDl cholesterol level showed a significant
decrease (11.7%, p<0.001) and alos maintained one month after Ramadan.
Mean body weight declined by 2.6% (p<0.1) on day 29 of Ramadan.
Saturated fatty acid intake decreased during Ramadan. Under the prevailing
conditions and feeding behavior of the subjects in the study, beneficial
affects of Ramadan fasting on plasma lipids and lipoproteins were noted.
Title: Pharmacists, medicines and
the fast of Ramadan
Authors: Mohamed Aslam and1 and John
Wilson2
Institution:
1 Senior Lecturer and Course Director in Clinical Pharmacy,
Department of Pharmaceutical Sciences, University of Nottingham,
2 Pharmaceutical Advisor to Nottingham Health Authority
Sources: Pharmaceutical Journal,
259:973-975, 1967
Abstract:
A review article. The authors concluded that a failure to comply with
prescribed dosage regimens during Ramadan can jeopardise the health of
Moslems with certain medical conditions. Pharmacists need to be aware of
the problems of their possible solutions.
Title: Effect pf Ramadan fasting on
intragastric pH recorded during 24 hours in healthy subjects
Authors: L. Iraki, A. Abkari, T
Vallot, N. Amrani, R.H. Khlifa, K. Jellouli and F. Hakkou
Institution: Fondation Hassan II
pour la Recherche Scientifique et Medicale sur le Ramadan, Casablanca,
Morocco
Source: Gastroenterol Clin Biol,
21(11): 813-819, 1967
Abstract:
The aim of this study was to evaluate the influence of Ramadan on gastric
acidity in healthy volunteers. Nine healthy volunteers had 24-hour
measurement of the gastric pH. The diurnal variations of the pH profile
were more significant; the median pH was 2.3 prior to Ramadan, 1 at day 10
and day 24, and 1.6 one month after Ramadan. The authors concluded that
the conditions of feeding imposed by Ramadan are associated with an
increase of the gastric acidity mainly in diurnal phase. The results do
not explain the origin of the healthy volunteer digestive symptoms
encountered during Ramadan.
Title: Ramadan diet restrictions
modify the circadian time structure in humans. A study on plasma gastrin,
insulin, glucose and calcium and on gastric pH.
Authors: L. Iraki1, A. Bodan2, F.
Hakkou1, N. Amrani3, A. Abkari4 and Y. Touitou2
Institution:
1 Hassan II Foundation for Scientific and Medical Research on
Ramadan, Faculte de Medecine et de Pharmacie, Casablanca, Morocco;
2 Faculte de Medecine Pittie-Salpetriere, 75013 Paris,
France;
3 Service d'Exploration Fonctionnelle Digestive, Hospital Ibn
Sina, Souissi, Rabat, Morocco;
4 Hospital Bnou Roch, Service de P3, Casablanca, Morocco.
Source: Journal of Clinical
Endocrinology and Metabolism, 82(1): 1261-1273, 1997.
Abstract:
A group of nine healthy male control subjects (mean age 25 and BW 73.3kg)
and six HDU ( healed duodenal ulcer) patients (mean age 39 and BW 64), who
were all healed from the ulcer for more than 3 months, were studied before
(controls), during and after the month of Ramadan. The protocol wa
approved by the Ethical Committee of the Faculte de Medecine and by the
religious board of the Hassan II Foundation for Scientific and Medical
Research on Ramadan. The time-restricted food and water intakes were
associated with variations o gastric pH, plasma gastrin, insulin, glucose,
and calcium documented on a cercadian basis. All of the studied biological
variables, except insulin, underwent changes in their 24-h mean
concentration (e.g. decrease in gastric pH, increase in plasma gastrin),
some of which were still present one month after the end of Ramadan. The
circadian patterns of all the studied variables were altered during the
month of Ramadan. The authors concluded that some differences between the
group of healthy control subjects and the HDUgroup may suggest a greater
susceptibility of the latter to the modifications of feeding and sleeping
schedule, which could possibly be a risk factor for the disease.

Title: Fasting and physiological
parameters: Time for standardization of research methodology
Authors: Layla Mammo1 and Jalal
Saour2
Institution:
1 Depaartment of Biological and Medical Research and
2 Department of Medicine, King Faisal Specialist Hospital and
Research Centre, Riyad, Saudi Arabia
Source: Research Centre Bulletin, A
Journal of Bilogical & Medical Research, 79(1&2):34-35, 1967.
Abstract:
A review article. Ramadan fasting entails major changes in sleep pattern,
physical activity and eating habits which may cause changes in metabolism
both in health and disease. Because of non-standardization of research
methodology, data available on Ramadan fasting is almost always
conflicting. Variables that are often overlooked or not reported include
the time of year and season when data were collected - in particular
whether Ramadan fell during long hot summer days or short cold winter
days. Further, the authors pointed that due to diverse social and economic
differences to expect identical results is unrealistic. However, it is
very clear that millions of healthy Moslems have fasted for many
generations without obvious ill effects.
Title: Beneficial effect on serum
apo AI, apo B and Lp AI levels of Ramadan fasting.
Authors: A. Adlouni, N. Ghalim, R.
Saile, N. Hda and A. Benslimane
Institution: Department de Biologie,
Faculte des Sciences Ben M'sik, Casablanca, Morocco
Source: Clin Chim Acta,
271(2):179-189, 1998
Abstract:
In a group of 32 healthy, volunteer adult males the levels of serum
apolipoproteins; apolipoprotein AI (Apo AI), apo B, apo AIV and those of
lipoprotein particles; apo AI-containing lipoprotein particles (Lp AI) and
also apo AII containing lipoprotein particles (Lp AI:AII), were determined
on each week of the month of Ramadan. The results were compared with the
pre-fasting and the post-fasting values. Ramadan fasting reduced
significantly serum apo B (p<0.05), while serum apo AI was
significantly increased (p<0.05) compared with the pre-fasting period.
The increase of apo AI occurred on day 29 of Ramadan by 11.8%. Serum apo
AIV was unchanged during the fasting period indicating that food intake
during Ramadan is not based on lipid diet. The observed diet pattern
during Ramadan showed an increase of total energy intake base on
carbohydrates(+1.4% of the total energy), proteins (+0.4% of total energy)
but not on fat (-0.7 of total energy), compared with a usual diet used in
the rest of the year. The fat diet was high in monounsaturated (p<0.05)
and polyunsaturated fatty acid in contrast to saturated fatty acid which
decreased (p<0.01) during Ramadan. Analysis of serum Lp AI and Lp
AI:AII showed that the levels of Lp AI:AII were unchanged but hose of Lp
AI were significantly increased (p<0.01) at the end of Ramadan. These
finding show that feeding behavior that occurs during Ramadan beneficially
affects serum apolipoprotein metabolism and may contribute to prevention
of cardiovascular diseases.
Title: Appetite changes under
free-living conditions during Ramadan fasting
Authors: G.M. Finch, J.E.L. Day,
Razak, D.A. Welch and P.J. Rogers
Institution: Department of Consumer
Sciences, Institute of Food Research
Source: Appetite 31(2):159-170, 1998
Abstract: A group of healthy Muslims
(15 men and 26 women) living in Reading, U.K. made hourly rating of their
hunger, mood and thirst, and recorded their food and drink intake on
specified days before, during and after Ramadan between January and March
1996. There were no significant changes in body weight over Ramadan. Rated
hunger increased substantially during the daily fast, and hunger was
higher for the women than the men during the earlier days of Ramadan,
whereas later, on average, fasting levels of hunger were very similar for
both sexes (significant gender x day interaction, p<0.01). During
Ramadan, the men tended to spend much of their time away from home, and
may therefore have largely avoided eating-related cues during the daily
fast. The women, however, were frequently involved in preparing food to be
eaten later after sunset, which suggests an explanation for the results
based on the external cue control of hunger. That is, unreinforced
exposure to food cues in this context may have led to a decrease in the
capacity of these cues to stimulate hunger.
Title: Variations of blood pressure
during the month of Ramadan
Authors: R. Habbal, L. Azzouzi, K.
Adnan, A. Tahiri, N. Chraibi
Institution: Centre de cardiologie,
Centre hospitalier universitaire Ibn Roch, Casablanca, Morocco
Source: Arch Mal Coeur Vaiss, 91(8):
995-998, 1998.
Abstract:
The study included 72 women and 27 men. From 1994 to 1997 the selected
hypertensive patients and their BP profile was studied. Their age varied
from 22 to 72 years (average 56.7±9). All these patients had an
ambulatory blood pressure measurement (ABPM) before the fast and during
Ramadan. Before Ramadan the period of the sleep was from 10 pm ±1 h to 8
am ± 1 h. During the month of Ramadan, the sleep lasts from 0 h±1 to 9
am ±1 h. No statistically significant difference was noted between these
two periods. The average hourly observations on 24 hours of the 99
patients was estimated. The authors observed that during the month of
Ramadan the peak of the awakening was delayed by two hours and the
nocturnal delayed by one hour. It was concluded that in patients with
essential hypertension without complications, the Ramadan fast is well
supported. The variations of BP are minimal and are related to the
variations of the sleep, activity and eating pattern.
Title: Gorging and plasma HDL-cholesterol--the
Ramdan Model.
Authors: M. Maislos, Y. Abou-Rabiah,
I Zuili, S. Iordash and S. Shany
Institution: Department of Medicine,
Toor Institute, Israel
Source: European Journal of Clinical
Nutrition. 52(2): 127-130, 1998
Abstract:
The objective of the study was to evaluate the effect of a single evening
meal (gorging) on plasma lipids and lipoprotiens in normal inidividuals
observing Ramadan fast. The study was conducted in the Bedouin town of
Rahat, in the northern Negevvarea of Israel. Twenty-two healthy subjects
who fasted during Ramadam and 16 non-fasting laboratory workers, were
studied before Ramadan, at week 1, 2 and 4 of the Ramadan month, an again
four weeks after the end of Ramadan.
Source:
International Journal of Ramadan Fasting Research
http://www.labs.net/ains/ramadan.htm
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